Regulation of Aurora B by Cdc48/p97 at the end of mitosis
During mitosis, the replicated genome is segregated into two daughter nuclei. The chromatin condenses into chromosomes followed by the breakdown of the whole nucleus. After sister chromatid segregation by the mitotic spindle, the nuclei reform in the daughter cells and cell division can be completed with cytokinesis. Chromatin needs to be segregated and repackaged into nuclei with high fidelity, since ...